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Old 10-20-2007, 05:38 PM   #321
harrie
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Join Date: Mar 2007
Location: Hilo, Hawaii
Posts: 1,867
For Kat in the delta...regarding the TOPO II and adriamycin. About 20% of br cancer diagnosis are HER2 elevated. Of those, they are either TOPO II positive or negative. If you are lucky enough to be TOPO II negative, then you will not need to receive the Adriamycin regimine. Instead you can go with a taxane such as taxotere which does not have the heart risk that adriamycin has.
I had gone for a second opinion on the chemo issue with Dr. Pegram who works in the same facility as Dr. Salamon. They are both very involved with the HER2 research and herceptin.
Maryanne
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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