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jml · 10-23-2011, 11:19 AM

Just wanted to share my 2cents worth...
The original tumor in my breast was only 2.5cms removed by lumpectomy, then when I had a local recurrence, in the exact same spot as the original, I had 1cm invasive lesion with DCIS, so that prompted the mastectomy.
However, the lesion in my liver, which started as a single spot, progressed to innumerable, immeasureable lesions that were clustered to gether, eventually was measured as one big lesion.

As for supplements, I'm on a array of vitamins & supplements & follow a very specific schedule as created for me by my TCM (traditional chinise medicine doc) that has been working with me since 6mos into my Stage IV dx. We must be on to something good bc here we are, 9 years later!

Keep the Faith~

Jml

Dx-5/17/02 - 33 yo; Stage IV
L IDC w/single liver met
Herceptin + Navelbine x 8 weeks - No response; progress to innumerable,immeasureable liver mets
ISIS 2504 + Herceptin - 6 mos, partial response
Taxol + Herceptin x 13 weeks to NED!
NED for 1 year
9/04 - Single liver lesion recurrence
Taxol + Herceptin - on/off to beat back lesion
12/05 - R Hepatectomy; Liver NED until 2009
3/06- Local recurrence - Left breast, IDC & DCIS, but holding treatment while continue to heal from Hepatectomy.
12/06 - L mastectomy + reconstruction through 8/07
10/07 - Recurrence - supraclav nodes
Gemzar + Herceptin - on/off controlling nodes thru
9/08 - 7wks rads to supraclav nodes
10/08 - Acute Renal Failure - nodes in belly stricturing kidneys. placed permanent ureteral stents
Back on Gemzar + Herceptin, but no longer responding.
05/09 - Tykerb + Xeloda - partial response x 5 mos
10/09 - Xeloda + Herceptin - no response, disease progresses
2/10- Ixempra + Herceptin - partial response x 12 wks.
Discovered single brain lesion x 4mm & liver lesions growing while screening for TDM1 + PI3Kinase study.
6/10 - Novalis to treat brain met - SUCCESSFUL!
6/10 - Chemo-embo w/Adriamyacin to de-bulk liver lesion.
8/10 - Screened & Started TDM1 EAP
Immediate response, disease in belly responds dramatically.
2/11- questionable progression of lung nodules
Discontinue TDM1
3/11 - PI3Kinase + Herceptin - intial good response in 1st 6 weeks but LFT's elevated.
7/11-Discontinue PI3Kinase + Herceptin study;
Disease progression - 2 small lesions in colon – docs have never seen this before in BC
8/11 –Start new combo Halaven+Herceptin
10/14/2011 -Completed 3 cycles (9 wks)Halaven+Herceptin...
10/18/2011 - Scanxiety time -1st scans since starting this regimen
10/20/2011 - re: scan results - "IT LOOKS REALLY GOOD!!!!!!!!!!!!"

10-23-2011, 11:19 AM	#6
jml Senior Member Join Date: Dec 2006 Posts: 415	Re: Questions Just wanted to share my 2cents worth... The original tumor in my breast was only 2.5cms removed by lumpectomy, then when I had a local recurrence, in the exact same spot as the original, I had 1cm invasive lesion with DCIS, so that prompted the mastectomy. However, the lesion in my liver, which started as a single spot, progressed to innumerable, immeasureable lesions that were clustered to gether, eventually was measured as one big lesion. As for supplements, I'm on a array of vitamins & supplements & follow a very specific schedule as created for me by my TCM (traditional chinise medicine doc) that has been working with me since 6mos into my Stage IV dx. We must be on to something good bc here we are, 9 years later! Keep the Faith~ Jml Dx-5/17/02 - 33 yo; Stage IV L IDC w/single liver met Herceptin + Navelbine x 8 weeks - No response; progress to innumerable,immeasureable liver mets ISIS 2504 + Herceptin - 6 mos, partial response Taxol + Herceptin x 13 weeks to NED! NED for 1 year 9/04 - Single liver lesion recurrence Taxol + Herceptin - on/off to beat back lesion 12/05 - R Hepatectomy; Liver NED until 2009 3/06- Local recurrence - Left breast, IDC & DCIS, but holding treatment while continue to heal from Hepatectomy. 12/06 - L mastectomy + reconstruction through 8/07 10/07 - Recurrence - supraclav nodes Gemzar + Herceptin - on/off controlling nodes thru 9/08 - 7wks rads to supraclav nodes 10/08 - Acute Renal Failure - nodes in belly stricturing kidneys. placed permanent ureteral stents Back on Gemzar + Herceptin, but no longer responding. 05/09 - Tykerb + Xeloda - partial response x 5 mos 10/09 - Xeloda + Herceptin - no response, disease progresses 2/10- Ixempra + Herceptin - partial response x 12 wks. Discovered single brain lesion x 4mm & liver lesions growing while screening for TDM1 + PI3Kinase study. 6/10 - Novalis to treat brain met - SUCCESSFUL! 6/10 - Chemo-embo w/Adriamyacin to de-bulk liver lesion. 8/10 - Screened & Started TDM1 EAP Immediate response, disease in belly responds dramatically. 2/11- questionable progression of lung nodules Discontinue TDM1 3/11 - PI3Kinase + Herceptin - intial good response in 1st 6 weeks but LFT's elevated. 7/11-Discontinue PI3Kinase + Herceptin study; Disease progression - 2 small lesions in colon – docs have never seen this before in BC 8/11 –Start new combo Halaven+Herceptin 10/14/2011 -Completed 3 cycles (9 wks)Halaven+Herceptin... 10/18/2011 - Scanxiety time -1st scans since starting this regimen 10/20/2011 - re: scan results - "IT LOOKS REALLY GOOD!!!!!!!!!!!!"