Two unrelated laboratory experiments indicate that on one hand Zometa enhance Fluvastatin (an approved anticholesterol drug also called Lescol) & on the other hand Fluvastatin enhances the activity of Herceptin.
All three drugs are approved & have relatively moderate side effects.
Could they be combined in treating breast cancer patients?
Anyone willing to ask her onc?
http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ProduktNr=223857&Ausgabe=231811&ArtikelNr=93006
Zoledronic Acid (Zometa®) Enhances the Cytotoxic Effect of Gemcitabine and Fluvastatin: In vitro Isobologram Studies with Conventional and Nonconventional Cytotoxic Agents
http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract
Fluvastatin enhancement of trastuzumab and classical cytotoxic agents in defined breast cancer cell lines in vitro