HER2 Support Group Forums - View Single Post - Endocrine Response Enhanced in ER+/PR+ Tumors

Hopeful · 11-10-2006, 03:13 PM

Here is the link: http://jcp.bmj.com/cgi/content/full/58/6/611 The title is "Association between tumour characteristics and HER-2/neu by immunohistochemistry in 1362 women with primary operable breast cancer."

The authors evaluated 1362 women from 2000-2003 in a single hospital in Belgium. The statistics they generated are very interesting. They concluded : "In women with ER+ tumours, the expression of PR affects the likelihood of HER-2/neu overexpression, and it may be that women with ER+ PR– tumours should be targeted with more aggressive treatment than those with ER+ PR+ tumours."

Hope this helps,

Hopeful

11-10-2006, 03:13 PM	#7
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Becky, I found the article I was looking for Here is the link: http://jcp.bmj.com/cgi/content/full/58/6/611 The title is "Association between tumour characteristics and HER-2/neu by immunohistochemistry in 1362 women with primary operable breast cancer." The authors evaluated 1362 women from 2000-2003 in a single hospital in Belgium. The statistics they generated are very interesting. They concluded : "In women with ER+ tumours, the expression of PR affects the likelihood of HER-2/neu overexpression, and it may be that women with ER+ PR– tumours should be targeted with more aggressive treatment than those with ER+ PR+ tumours." Hope this helps, Hopeful