[TanyaRD]

Sure. Some studies have demonstrated that in combination with certain chemotherapy agents the polyphenols in green tea actually inhibit the therapeutic effect of the chemo, or make is less effective. This has especially been seen in drugs used to treat multiple myeloma and lymphoma (i.e. Velcade) and hasn't been well studied with other drugs. Given this conclusion it is advised that green tea should be used with caution. Supplemental form offers a much higher dose than a single cup of tea and thus poses as higher risk for interaction. Secondly, green tea supplements are a very concentrated source of antioxidants. While antioxidants are beneficial in many ways, they also are very effective at protecting cell walls. Some studies have shown that high antioxidants in combination with certain chemotherapy agents called alkylating agents (often used to treat breast cancer) may protect the cell walls of cancer cells and prevent the drug from being as effective.

The bottom line is that high doses of antioxidants in supplemental form are not recommended during chemotherapy. The amount in a healthy diet with fruits and vegetables is not concerning. I feel comfortable with my breast cancer patients drinking a couple cups of green tea per day but discourage green tea supplements.