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Re: Neratinib Clinical Trial
That is interesting Chelee. That makes me feel even better about my onc, since she was the first one who suggested the Tykerb/Herceptin combo. I also talked to her the other day about the UCSF trial with Neratinib. She would be behind either option, but also really wants to know what Slamon thinks. It does make sense that I can't work backwards. If I try the trial, I can always switch to Tykerb/Herceptin, but I can't do it the other way around if the combo doesn't work, or I progress on it. Taking Tykerb automatically disqualifies me from the trial. Decisions, decisions! I am just feeling so blessed that I have options like this.
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March 2010: Diagnosed with Stage IIIC IDC with axillary, mammary and suplaclavicular node involvement. ER/PR -, HER2+++. 7cm tumor in right breast.
April 2010: Started neoadjuvent chemo. 4 DD A/C every 2 weeks, 4 DD Taxotere every 3 weeks with Herceptin weekly.
August 2010: Finished chemo!
August 20, 2010: PET/CT showed no cancer in any nodes, and only a little uptake to the breast.
September 9, 2010: Bilateral mastectomy with immediate reconstruction with implants and Alloderm.
September 16, 2010: Pathology report showed 18/51 positive axillary nodes, 3.2cm tumor. Granual sized cancer found in the fatty tissue between levels 1 and 2.
October 19, 2010: CT showed several spots on lungs and 1 spot on liver. Liver spot is 2mm, lung spots range from 2mm to 4mm. We don't know if they are cancer or not.
12/15/10: Brain MRI clear
1/7/11: PET/CT
1/13/11: Recurrence in lungs. Start Tykerb
5/13/11: Progression in lungs
6/3/11: Lung surgery to get tumors for chemosensitivity testing.
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