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Old 02-01-2011, 10:02 AM   #4
TanyaRD
Senior Member
 
Join Date: Sep 2009
Posts: 358
Re: Green Tea/epigallocatechin-3-gallate (EGCG)

Rich,
There is one study that "stopped us in our tracks" so to speak in regards to green tea and I have pasted it below. Prior to this study I highly recommended green tea to my patients during treatment. This study caused all of us to examine that recommendation and the decision was made to have patients avoid large amounts of green tea (occasional cup ok) and none for those on Velcade. This was a difficult decision to make and possibly over cautious but one we felt justified until further evidence is available to provide assurance that there will be no interaction/decreased efficacy when used in conjunction with chemotherapy.

Blood. 2009 Jun 4;113(23):5927-37. Epub 2009 Feb 3.
Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors.

Golden EB, Lam PY, Kardosh A, Gaffney KJ, Cadenas E, Louie SG, Petasis NA, Chen TC, Schönthal AH.
Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA 90089-9094, USA.
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TanyaRD

Registered Dietitian
Board Certified Specialist in Oncology Nutrition
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