HER2 Support Group Forums - View Single Post - Warning,careful! Need/advisability of mastectomy in her2+breast cancer

saleboat · 05-17-2006, 01:53 PM

Hi Lani,

"In patients with positive nodes and HER2-positive tumours the estimation of the time-dependent log-hazard ratios showed that radical mastectomy significantly increased early death rates (P = 0.037)"

Am I reading this correctly? Does this mean that radical mastectomies were associated with early death rates? I guess I'm confused, but I'm not much of a statistician.

Thanks for any light you can shed.

Jen

05-17-2006, 01:53 PM	#3
saleboat Senior Member Join Date: Sep 2005 Location: NYC Posts: 250	Hi Lani, "In patients with positive nodes and HER2-positive tumours the estimation of the time-dependent log-hazard ratios showed that radical mastectomy significantly increased early death rates (P = 0.037)" Am I reading this correctly? Does this mean that radical mastectomies were associated with early death rates? I guess I'm confused, but I'm not much of a statistician. Thanks for any light you can shed. Jen __________________ dx 4/05 @ 34 y.o. Stage IIIC, ER+ (90%)/PR+ (95%)/HER2+ (IHC 3+) lumpectomy-- 2.5 cm 15+/37 nodes (IVF in between surgery and chemo) tx dd A/C, followed by dd Taxol & Herceptin 30 rads (or was it 35?) Finished Herceptin on 7/24/06 Tamox livingcured.blogspot.com "Keep your face to the sunshine and you cannot see the shadow." -- Helen Keller