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Old 02-24-2010, 07:46 PM   #8
LoriG
Senior Member
 
Join Date: Jan 2010
Posts: 28
Re: Tykerb/Xeloda, side effects??

Thanks, Ellie!

Liz, The T/X combo is very tolerable. My biggest definite side effect is the little cuts I get on the ends of my fingers...very annoying but in the grand scheme of things not a big deal. I have been fortunate to not have any diarrhea and only a brief episode of the rash. Last week I had 2-3 days of constant and very disturbing palpitations (premature ventricular contractions on EKG). This bought me a CT of my chest to rule out pulmonary embolus. Luckily it was normal...no PE, no fluid in my lungs, no signs of lung mets. I see my onc this week and will likely need an echo to look for a chemo-induced cardiomyopathy. I also read xeloda can causes arrythmia issues. I am off the xeloda this week and the palpitations have resolved. I am really hoping the xeloda is not the cause because it is working , and I don't want to stop it! As for the blurred/double vision I think I will be requesting a brain MRI. My near vision as gone to total h*ll. I had some blurry vision issues with Taxol but nothing like this.

I hope you do well on this combo! Thanks for your response!
__________________
Lori, age 33
*IBC (ER+,PR-,Her2+) on right diagnosed 8/09 with metastatic lymph node left axilla (Er-,PR-,Her2+) vs possible bilateral breast cancer
*A/C x4
*Taxol x4 with weekly herceptin
*Breast MRI 12/09- no improvement
*PET scan 12/09- no evidence of mets
*Tykerb/Xeloda 12/09
*Bilateral MRM 4/10
*Twice daily rads to both chest walls and both axillas 5/10-6/10
*9/10 PET/CT- NED
*Tykerb/Xeloda until 12/10
*Tykerb and Tamoxifen 12/10-current. Bye bye Xeloda
*2/11- malignant pleural effusions bilaterally (likely lymphangitic lung mets) and skin mets
Herceptin and Ixempra
LoriG is offline   Reply With Quote