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Old 07-21-2013, 04:52 AM   #24
KristinSchwick
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Join Date: Jun 2011
Location: Iowa
Posts: 231
Re: Cancer secret to success?! Finding your match!

I can sense you have a great deal of background on this subject, are you a researcher yourself? Myself, I have a Doctorate in Immunology, so I completely agree with you on a research level, but from a BC patient perspective, I believe more options are needed because not all cancers are solid, and are able to be sampled in this fashion. It sounds like the dream clinical trial, but it would need to be done on breast tissue from early stage patients (I-III), as there would be too many variables in other organ metastases. As a former researcher, I think this is a awesome idea, and I have participated in some projects looking at the tumor micro environment and it is an area that needs more attention as it is so complex.

I would just like to see some microarray trials soon to see if on a mRNA level, we can learn about drug sensitivity that way too.

Cheap to the researcher and cheap to the patient are two different things. For me personally, I can not donate a whole gram of my pelvis while alive, but would gladly donate my primary tumor of the breast except it is in paraffin and not viable. Hopefully they are able to collect enough specimens to fulfill this study, as the results could benefit all cancer patients like you said.

Kristin
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[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/

Last edited by KristinSchwick; 07-21-2013 at 04:57 AM.. Reason: More detail
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