[RobinP]

In 2004, physicians reported that women who took Fosamax for 10 years (with a 10-milligram dose) saw an increase in lower-spine density of about 14 percent. While the drugs appear safe, scientists can't say whether the suppression of bone turnover might cause long-term side effects.


I am weary over the question concerning long term affects for biphosphonates. While I do think the biphosphonates are great for severe bone loss, bone mets and pagets disease, I really the question the use of these drugs in less severe cases like osteopenia where other interventions may be just as effective in strenghting bone. I just hope the long track record for biphosphonates doesn't turn out like Hormal replacement therapy.