HER2 Support Group Forums - View Single Post - complicated new article on the origins/pathways gone awry in Inflammatory BC

Roz · 09-01-2007, 11:54 PM

I found this quite hard to follow Lani, but thank you for posting it. I am ER+ and IBC. I was 56 when diagnosed, 5 years past menopause. I am wondering whether or not I should have my ER tested again, as I have a sneaking suspicion that I might have only a little bit of +. If I read this article correctly, ER downregulation should mean ER-??

09-01-2007, 11:54 PM	#3
Roz Senior Member Join Date: Oct 2005 Location: Sydney Australia Posts: 105	I found this quite hard to follow Lani, but thank you for posting it. I am ER+ and IBC. I was 56 when diagnosed, 5 years past menopause. I am wondering whether or not I should have my ER tested again, as I have a sneaking suspicion that I might have only a little bit of +. If I read this article correctly, ER downregulation should mean ER-?? __________________ diagnosed June 03. Rt sided Inflammatory BC in rt lower quadrant. 7cm tumour. Also 3 DCIS. 3 rounds of EC, mastectomy with axillary clearance (12 nodes+ of 19). 1 more EC. 5 weeks of rads, with weekly booster to attack skin lymph involvement. 4 cycles of Taxol. Tamoxifen.Recurrence December 04, Herceptin started early Jan05,+ Arimidex. NED 26 mths. Recurrence early Mar07. Taxol added to Herceptin. NED. Will have total of 6 cycles, then Aromisan and Herceptin. Early Oct 07, recurrence to the pesky right upper lobe, with some pleural thickening upper rt hemithorax. T/X now the treatment. May 2008, Taxatere and Herceptin for lung recurrence