HER2 Support Group Forums - View Single Post - MUST READ-- metastatic her2+ breast cancer not necessarily the death sentence it was

Lani · 07-08-2012, 05:00 AM

Yes, MJs husband, you are missing something. These are not Stage IV statistics for all Stage Ivs treated everywhere, but just for Stage IVs treated in their two groups of patients ie, Dublin and Milan.

And even within those two groups the stats differ as the "institutional policy" was such that Stage IV patients in Dublin continued on trastuzumab until progression or at least for five years whereas in Milan, trastuzumab was generally stopped in CR patients within two years of achieving remission.

If you reread the abstract with that in mind, it makes more sense and is another piece of evidence that continuing herceptin beyond progression(and just adding things) is the way to go.

07-08-2012, 05:00 AM	#6
Lani Senior Member Join Date: Mar 2006 Posts: 4,778	Re: MUST READ-- metastatic her2+ breast cancer not necessarily the death sentence it Yes, MJs husband, you are missing something. These are not Stage IV statistics for all Stage Ivs treated everywhere, but just for Stage IVs treated in their two groups of patients ie, Dublin and Milan. And even within those two groups the stats differ as the "institutional policy" was such that Stage IV patients in Dublin continued on trastuzumab until progression or at least for five years whereas in Milan, trastuzumab was generally stopped in CR patients within two years of achieving remission. If you reread the abstract with that in mind, it makes more sense and is another piece of evidence that continuing herceptin beyond progression(and just adding things) is the way to go.