HER2 Support Group Forums - View Single Post - Adjuvant herceptin 6 months vs 12 months?

Mandamoo · 03-31-2012, 04:32 PM

Thanks Becky - there seems to be a trial - UK based I think called Persephone - no results published yet but I believe it has finished recruiting and results are due soon - I thought someone may have some inside knowledge. I guess with all of these trials to get a decent results takes time especially when we are looking at recurrence rates - we want to be looking at 5 years+ and it is just too soon to have those results that are meaningful yet.

If you are self funding herceptin though - 6vs 12 months is a considerable saving financially but you would want some assurance that the overall benefit was similar.

I agree - it would be good to have follow up off those who have stopped herceptin under 12 months to see what recurrence rates are like.
Thanks for your response.
Amanda x

03-31-2012, 04:32 PM	#4
Mandamoo Senior Member Join Date: Jul 2011 Location: Melbourne, Australia Posts: 432	Re: Adjuvant herceptin 6 months vs 12 months? Thanks Becky - there seems to be a trial - UK based I think called Persephone - no results published yet but I believe it has finished recruiting and results are due soon - I thought someone may have some inside knowledge. I guess with all of these trials to get a decent results takes time especially when we are looking at recurrence rates - we want to be looking at 5 years+ and it is just too soon to have those results that are meaningful yet. If you are self funding herceptin though - 6vs 12 months is a considerable saving financially but you would want some assurance that the overall benefit was similar. I agree - it would be good to have follow up off those who have stopped herceptin under 12 months to see what recurrence rates are like. Thanks for your response. Amanda x __________________ Amanda xx 40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11 Wife to my wonderfully supportive husband of 17 years! 22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old (L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins. Fec3, Taxotere and herceptin2 - stopped due to secondary diagnosis June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy! September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing. January 2013 - herceptin, carboplatin and Perjeta (compassionate access) April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.