HER2 Support Group Forums - View Single Post - Herceptin Joint Pain

12-29-2011, 10:05 AM

Hi All,

Thanks for sharing all the valuable info about herceptin. Last month when my mother had pain after herceptin treatment I was looking for the same information.

My mother was treated with Herceptin+Xeloda with 1st dosage of 8mg/kg. Incidentally there was no pain after the first cycle. During the second cycle, doctors reconstituted the remaining herceptin from first cycle with saline. There was severe joint and bone pain after the second cycle.

I read through these blogs and asked the doctor to administer a fresh batch of herceptin every cycle, as the batch size of 440 mg is almost equal to one cycle's requirement.

The third round onwards, there is no pain. It is to be noticed that the second round which caused pain was also reconstituted using saline only, and not benzyl alcohol. So it seems that the pain is caused by part usage of one batch regardless of the mode of reconstitution.

She has undergone her 4th cycle as well last week and is fine with regard to bone and joint pain.

Hope it helps someone.

12-29-2011, 10:05 AM	#55
Unregistered Guest Posts: n/a	Re: Herceptin Joint Pain - Does it last the whole year?? Hi All, Thanks for sharing all the valuable info about herceptin. Last month when my mother had pain after herceptin treatment I was looking for the same information. My mother was treated with Herceptin+Xeloda with 1st dosage of 8mg/kg. Incidentally there was no pain after the first cycle. During the second cycle, doctors reconstituted the remaining herceptin from first cycle with saline. There was severe joint and bone pain after the second cycle. I read through these blogs and asked the doctor to administer a fresh batch of herceptin every cycle, as the batch size of 440 mg is almost equal to one cycle's requirement. The third round onwards, there is no pain. It is to be noticed that the second round which caused pain was also reconstituted using saline only, and not benzyl alcohol. So it seems that the pain is caused by part usage of one batch regardless of the mode of reconstitution. She has undergone her 4th cycle as well last week and is fine with regard to bone and joint pain. Hope it helps someone.