[donocco]

Flori

Its late so I can only give you a shoot from the hip answer. If you infuse slowly the blood level of the drug will rise more slowly. Side effects are often associated with the blood level. Im guessing but take an oral drug like Benadryl that causes drowsiness. If you take two Benadryl caps at once you will get more drowsy because the blood levels will be higher.

Im not sure if the same idea applies to allergic reactions but it might. Take Penicillin. Most serious anaphylactic reactions have occurred when the drug was injected and the blood levels increased quickly. Oral Penicillin allergic reactions are more often expressed as rashes or hives. If a patient tells a pharmacist he, she is allergic reaction the highest percentages were oral not iv experiences ie rashes. In fact if you study a book on drug interactions there is an interesting one between the anti-Uric acid drug Allopurinol and Amoxicillin. Taken together there can be rashes and the patient is wrongly considered to be allergic to Penicillin.

Oral allergies can be very serious though ie to peanuts etc. Everything is debatable.

Ill do more thorough research tomorrow to see if I can find any more info. Im also going to research that experimental drug pyrotinib.

Glad youve made up your mind and can breathe a bit easier

Paul