HER2 Support Group Forums - View Single Post - Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastases)

dchips1 · 01-24-2014, 11:50 PM

Hi Mario I am glad Carol is doing better. Evilin I am glad daughter feeling better as well. Thanks Paulfor leading the way.
I am having surgery to debulk and remove the t 8 lesion and fluid on the 29th. Neuro symptoms are rapidly getting worse. with no quick IT drug available this is what My family and medical team have decided to do. Cool thing is it will be done in Phoenix at Barrows Neurological institute, world class neuro drs and some really good technology and inpatient neuro rehab. since I am already his patient was able to get in very quick. The fluid has pushed the lesion more toward the right side laminectomy style. Best case coming out weak, which I already am, but should stop the growth and stop further nerve damage. Then go back to IT/IV herceptin

Peace and Prayers to all
I will update when they let me have my electronics back!!!!!

01-24-2014, 11:50 PM	#165
dchips1 Senior Member Join Date: May 2006 Location: Mesa, Az Posts: 219	Re: Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastase Hi Mario I am glad Carol is doing better. Evilin I am glad daughter feeling better as well. Thanks Paulfor leading the way. I am having surgery to debulk and remove the t 8 lesion and fluid on the 29th. Neuro symptoms are rapidly getting worse. with no quick IT drug available this is what My family and medical team have decided to do. Cool thing is it will be done in Phoenix at Barrows Neurological institute, world class neuro drs and some really good technology and inpatient neuro rehab. since I am already his patient was able to get in very quick. The fluid has pushed the lesion more toward the right side laminectomy style. Best case coming out weak, which I already am, but should stop the growth and stop further nerve damage. Then go back to IT/IV herceptin Peace and Prayers to all I will update when they let me have my electronics back!!!!! __________________ dx 1/06 IDC 2cm 38 at dx 2/06 L mast nodes 3/9+ SNB neg ER-/Pr - her2 + Stg 4 liver/pelvis 3/06-9/06Taxol/Carbo/zometa/Herceptin 3/07 6 brain mets WBR down to c-2 4/07 osteonecrosis jaw 1/08 mri new 9mm lesion right lower side 2/08 gamma knife 1 lesion 11/08 regamma 10/09 latent rad necrosis to brain met, 1/20/10 crani: lesion necrosis w active cells continue her add tykerb 1/11 NED just Ingrown toenail! YEAH GOD 8/11 Tykerb, herceptin weekly, elevated her2 levels, negative scans oct -march 11 new neuro deficits lower legs 3/12 2 spinal metsTykerb, Herceptin 04/12 4050cGY rads T 2-4 & T7-9 5/12 Brain,cervical lumbar clear/thoracic slight decrease 10/12 t 2-4 shrunk t-9 grew start Xeloda, 02/13 stop xeloda,5/13 on metformin, decadron, Tykerb, iv and IT herceptin 5/30/13 total #11 #2 of 80mg dose weekly. 9/13 100mg of IT her, IV hern, 750 mg tykerb, 3mg dec. last Mri T--3 SHRUNK t7-9 shrunk no edema. Left shift in CBC bone marrow BX negative. 10/13 Ct has shown Double left ureters with stones/cysts in them, after 3 births and lots and U/S iit takes cancer to figure out you have 2 smaller ureters going into 1 kidney! 12/13 Mri brain no new lesions, cervical and lumbar arthritis. Tspine lesion at T3 stable, T 7-9 GROWTH lots of pain 1/29/14 HIHO HIHO its off to Neuro surgery I go Life is Good when you wake up in the morning and take a breath and know that God has given me another day.