A mechanism beyond the level of gene regulation, which is often the underlying reason for changes in protein levels, does enable the strong accumulation of a tumour promoting protease in stressed cancer cells. The group of BIOSS researcher Prof. Dr. Thomas Reinheckel teamed up with BIOSS investigator Prof. Dr. Sabine Rospert and their colleagues from the University Medical Center Freiburg, Prof. Dr. Elmar Stickeler and Dr. Peter Bronsert, in order to unravel mechanisms by which stress-resistant production of cancer promoting proteins occurs.
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