['lizbeth]

@Linn65,

A quick look - I can't describe your neoadjuvant as progression. I do see the cancer adapting to the changes in the environment caused by neoadjuvant treatment. I do not see the information available about the nodes prior to treatment. Did you have PET done prior to chemo?

Lani had talked about this in a prior post about the vaccines - Her2 changing to Triple Negative. In your case the cells became more expressed in ER.

Perhaps we should explore a bit more about ER positive cancers in a new thread. I'll start one a little later.

Hugs my friend.