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7andcounting · 06-01-2012, 06:46 PM

Hello All,

Well the fun just never stops. Just when I think I know the plan, life springs new things on me.

I just got through jumping through all the hoops to qualify to be on the TDM-1 trial. Got my tissue sample verified that I was Her2+, had every scan imaginable and thought I was all set to be randomized to one of the arms of the trial, when I got a call that my heart function was very low.

Shock!

I have been having echos every 3 months and all was fine. I asked to have a MUGA to confirm that the echo was correct, b/c it didn't seem possible that my heart function could have deteriorated that much, but the MUGA confirmed that it was indeed true.

My question is: Has anyone had their heart function drop significantly, then gone off Herceptin for a few months and then had their heart return to better levels that let them resume their Her2+ targeted therapies?

Any insight is appreciated!

Thanks!

06-01-2012, 06:46 PM	#1
7andcounting Senior Member Join Date: Jun 2011 Posts: 107	Bad heart news.....wah!!!!!!!! Hello All, Well the fun just never stops. Just when I think I know the plan, life springs new things on me. I just got through jumping through all the hoops to qualify to be on the TDM-1 trial. Got my tissue sample verified that I was Her2+, had every scan imaginable and thought I was all set to be randomized to one of the arms of the trial, when I got a call that my heart function was very low. Shock! I have been having echos every 3 months and all was fine. I asked to have a MUGA to confirm that the echo was correct, b/c it didn't seem possible that my heart function could have deteriorated that much, but the MUGA confirmed that it was indeed true. My question is: Has anyone had their heart function drop significantly, then gone off Herceptin for a few months and then had their heart return to better levels that let them resume their Her2+ targeted therapies? Any insight is appreciated! Thanks!