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Old 12-10-2013, 07:28 AM   #1
Hopeful
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Join Date: Aug 2006
Posts: 3,380
ultra-deep targeted sequencing for personalized bc care

http://breast-cancer-research.com/co...df/bcr3584.pdf

At page 13:

Quote:
Looking at somatic mutations and amplification, we would have proposed the use of Trastuzumab for 7 patients based on ERBB2 status. Notably, for one of them the ERBB2 gene is not amplified but carried an activating mutation, which would have been missed through standard Her2 testing.


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