HER2 Support Group Forums - View Single Post - Pertuzumab not avaliable to stage 4 contrary to what you have heard

Mandamoo · 07-21-2012, 02:31 PM

I have a meeting with my oncologist on Tuesday. I am awaiting the results of my lung biopsy.
I have a few things on the list. I am fortunate to have a very good contact at Roche (Genentech in Australia) who hinted at the possibility of access to pertuzamab but I don't want to get my hopes too high as I don't understand how I could if there is no TGA approval here - apparently it will depend on my prior treatment. We are struggling to find me a tumor big enough to gain access to the Theresa trial - one radiologist reckons he can, 2 others not. My onc is off at a clinical trials conference this weekend so hopefully she will come back with a couple of good ideas.
I am now on Tykerb only until we have a plan. giving myself a xeloda rest which is pleasant. Hoping to also still have our trip to Italy with the kids which was booked for September but may bring it forward.
I feel calm and well so I am going with that feeling.
Xxx

07-21-2012, 02:31 PM	#42
Mandamoo Senior Member Join Date: Jul 2011 Location: Melbourne, Australia Posts: 432	Re: Pertuzumab not avaliable to stage 4 contrary to what you have heard I have a meeting with my oncologist on Tuesday. I am awaiting the results of my lung biopsy. I have a few things on the list. I am fortunate to have a very good contact at Roche (Genentech in Australia) who hinted at the possibility of access to pertuzamab but I don't want to get my hopes too high as I don't understand how I could if there is no TGA approval here - apparently it will depend on my prior treatment. We are struggling to find me a tumor big enough to gain access to the Theresa trial - one radiologist reckons he can, 2 others not. My onc is off at a clinical trials conference this weekend so hopefully she will come back with a couple of good ideas. I am now on Tykerb only until we have a plan. giving myself a xeloda rest which is pleasant. Hoping to also still have our trip to Italy with the kids which was booked for September but may bring it forward. I feel calm and well so I am going with that feeling. Xxx __________________ Amanda xx 40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11 Wife to my wonderfully supportive husband of 17 years! 22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old (L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins. Fec3, Taxotere and herceptin2 - stopped due to secondary diagnosis June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy! September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing. January 2013 - herceptin, carboplatin and Perjeta (compassionate access) April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.