HER2 Support Group Forums - View Single Post - Well Poop

chrisy · 04-17-2009, 05:33 PM

Lori,

Well POOP
I guess you've correctly described MY feelings on this as well!

Sounds like you are getting lots of good advice and options. If it were me and I was dealing with a single met, I'd look at the local options - yes, it is Esther/luv2ski who had the cyberknife done on her liver met, it's not commonly done but she did it at Stanford.

I'm not familiar with the option Rich has posted, but it sounds close to you and worth looking into, especially if you know swedish. Or maybe you just need to like big fluffy pancakes...

Finally, I'd like to offer this thought on the chemo options. I agree with what you say about not changing chemos - going back to the "winning horse". On the other hand, you've had such a good response to Herceptin you would be a great candidate for a DM1 trial. I wouldn't rule that out.

My doctor at UCSF who is one of the cutting edge researchers in BC is a very big advocate of using targeted therapies and avoiding chemo as much as possible. Keeping your body and immune resources strong is so important.

Lori, I'm bummed that you are having to deal with this, but it is what it is,so now your goal is to MANAGE it...as I know you will.

Hang in there, keep us posted!

04-17-2009, 05:33 PM	#9
chrisy Senior Member Join Date: Sep 2005 Location: Central Coast, CA Posts: 3,207	Lori, Well POOP I guess you've correctly described MY feelings on this as well! Sounds like you are getting lots of good advice and options. If it were me and I was dealing with a single met, I'd look at the local options - yes, it is Esther/luv2ski who had the cyberknife done on her liver met, it's not commonly done but she did it at Stanford. I'm not familiar with the option Rich has posted, but it sounds close to you and worth looking into, especially if you know swedish. Or maybe you just need to like big fluffy pancakes... Finally, I'd like to offer this thought on the chemo options. I agree with what you say about not changing chemos - going back to the "winning horse". On the other hand, you've had such a good response to Herceptin you would be a great candidate for a DM1 trial. I wouldn't rule that out. My doctor at UCSF who is one of the cutting edge researchers in BC is a very big advocate of using targeted therapies and avoiding chemo as much as possible. Keeping your body and immune resources strong is so important. Lori, I'm bummed that you are having to deal with this, but it is what it is,so now your goal is to MANAGE it...as I know you will. Hang in there, keep us posted! __________________ Chris in Scotts Valley June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?" 9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++ 10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response! 04/05 - 4/07 Herception every 3 wks, Continue NED 04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial 06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin 01/08 Progression in liver 02/08 Begin (TDM1) trial 08/08 NED! It's Working! Continue on TDM1 02/09 Continue NED 02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED 12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver 07/11 - 11/11 Herceptin/Xeloda -not working:( 12/11 Begin MM302 Phase I trial - bust:( 03/12 3rd times the charm? AKT trial 5/12 Scan shows reduction! 7/12 More reduction!!!! 8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!) 9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3 11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc 11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go. 2/13 Gemzar/Carbo/Herceptin - no go. 3/13 TACE procedure