[Becky]

I am using the estring too. I am not that much ER+ and PR-. After the ooph and Arimidex, besides the vaginal atrophy and dryness, I had never ending bladder infections. My onc and surgeon were gun ho for the estring (which I am using now) but my gyne preferred the premarin cream. I opted for the estring due to lack of messiness.

For me this thread is extremely timely. I am nearing 5 months on the estring and the first estring (for those that don't know - they last 90 days), it was like a miracle. I wanted to call my onc St. Myron but it is not as effective as before. Until I read this thread, I thought I might have gotten a "bum" ring but now I don't think so. If it keeps up this way, maybe I will switch to the messier cream if it works better. However, my onc did say that the estring is the only "allowed" vaginal product to use if you are in clinical trials. Also, it is the only featured product in conferences for oncs on quality of life issues/topics. It is very safe (according to them).

I did have my estrogens measured before insertion (I asked to have this done) and I got them measured again after 2 months and got the exact same readings. This greatly reassured me. I am just a bit concerned as it doesn't seem as effective. I did have my "yearly" with the gyne and he said my vagina looked nice and healthy with lots of adult cells sloughing off and it was not that way before (as I was going there with the UTIs and some vaginal soreness/infections due to atrophy).

Oh well - at least no UTIs and that is a huge blessing.