HER2 Support Group Forums - View Single Post - Intrathecal Herceptin/Topotecan for Leptomeningeal Disease

Rolepaul · 05-16-2012, 07:06 AM

Potra,

Have them contact the main center in Houston Texas. Dr. Loghin is the neurooncologist and Dr. Melhem-Bertrandt is the breast oncologist. This was a compassionate care treatment, but I think they want to get a full study going. There are a tremendous number of patients and it was noted in 2007 that this was going to occur with Herceptin and brain involvement. 30% of all HER patients have your situation, and in the past there was not a good method to treat it. This appears to work for a couple of patients, now it is time for more women to be treated with this. It is not inexpensive, but it has a good chance of working based on the results I have seen with Nina and with others that are not in major publications. I hope this is a road map for many more patients that are on this blog.

05-16-2012, 07:06 AM	#7
Rolepaul Senior Member Join Date: Jan 2012 Location: Boulder Colorado as of January 2013 Posts: 389	Re: Intrathecal Herceptin/Topotecan for Leptomeningeal Disease Potra, Have them contact the main center in Houston Texas. Dr. Loghin is the neurooncologist and Dr. Melhem-Bertrandt is the breast oncologist. This was a compassionate care treatment, but I think they want to get a full study going. There are a tremendous number of patients and it was noted in 2007 that this was going to occur with Herceptin and brain involvement. 30% of all HER patients have your situation, and in the past there was not a good method to treat it. This appears to work for a couple of patients, now it is time for more women to be treated with this. It is not inexpensive, but it has a good chance of working based on the results I have seen with Nina and with others that are not in major publications. I hope this is a road map for many more patients that are on this blog.