HER2 Support Group Forums - View Single Post - worried: bumps on scar line

Aussie Girl · 02-17-2014, 04:31 AM

Dear Alice

I can only find a rare case (about 3 cases) of possible progression of AVL to angiosarcoma. It has been thought the "vascular type" of AVL rather than the more common "lymphatic type" AVL may rarely progress.

However recent studies suggest the AVL lack a particular mutation (called a MYC mutation) which is found in angiosarcoma -so the two may not be related at all.

AVL is becoming more common, possibly because of changes in the way radiation is given these days.

Hope that helps. Overall an AVL doesn't appear to be too serious.

Aussie Girl

02-17-2014, 04:31 AM	#12
Aussie Girl Senior Member Join Date: Jul 2013 Posts: 260	Re: worried: bumps on scar line - biopsy indicates allergy Dear Alice I can only find a rare case (about 3 cases) of possible progression of AVL to angiosarcoma. It has been thought the "vascular type" of AVL rather than the more common "lymphatic type" AVL may rarely progress. However recent studies suggest the AVL lack a particular mutation (called a MYC mutation) which is found in angiosarcoma -so the two may not be related at all. AVL is becoming more common, possibly because of changes in the way radiation is given these days. Hope that helps. Overall an AVL doesn't appear to be too serious. Aussie Girl __________________ 31mm Infiltrating duct carcinoma Grade 3, ER/PR-, HER2+, Neg Sentinel nodes x 5 49mm field of DCIS 17 June '13: Screen detected impalpable mass, Mammogram neg, US. 25 June '13: Diagnosed after multiple biopsies and MRIs 28 June '13: Left lumpectomey 4 July '13: Left Mastectomy 12 August '13: Commenced TCH chemo Mid December '13 : TCH finished. Herceptin continuing three weekly. 4 August 2014- Herceptin infusions finished. END OF THERAPY - YAY!