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R.B. · 10-14-2019, 01:47 PM

Endocannabinoid Signaling in Female Reproduction

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382454/

"Since then, numerous studies have been published on cannabinoid signaling in female reproductive events, including preimplantation embryo development, oviductal embryo transport, embryo implantation, placentation, and parturition."

"almost all pregnancy events are regulated by endocannabinoid signaling, and in most cases, optimal outcomes can only be achieved under normal physiological endocannabinoid levels. Either silenced or enhanced endocannabinoid signaling derails these processes. This is a trait of endocannabinoid signaling that provides a route for medical manipulation in each pregnancy event. However, the in-depth mechanism by which endocannabinoid signaling exerts its role is still not clear. In addition, it would be interesting to study the mechanism behind how lower and higher cannabinoid signaling generates similar phenotypes. Further studies on endocannabinoid signaling with respect to female reproduction will generate new molecular mechanisms governing pregnancy events."

10-14-2019, 01:47 PM	#10
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Re: Cannabinoid receptors – main ligands are Omega 3 and 6 derivatives, not hemp prod Endocannabinoid Signaling in Female Reproduction https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382454/ "Since then, numerous studies have been published on cannabinoid signaling in female reproductive events, including preimplantation embryo development, oviductal embryo transport, embryo implantation, placentation, and parturition." "almost all pregnancy events are regulated by endocannabinoid signaling, and in most cases, optimal outcomes can only be achieved under normal physiological endocannabinoid levels. Either silenced or enhanced endocannabinoid signaling derails these processes. This is a trait of endocannabinoid signaling that provides a route for medical manipulation in each pregnancy event. However, the in-depth mechanism by which endocannabinoid signaling exerts its role is still not clear. In addition, it would be interesting to study the mechanism behind how lower and higher cannabinoid signaling generates similar phenotypes. Further studies on endocannabinoid signaling with respect to female reproduction will generate new molecular mechanisms governing pregnancy events." Last edited by R.B.; 10-14-2019 at 02:05 PM..