[radiant]

Hi Nancy and others!

I started t-dm1 last week in Stockton as well. I would have to say my first dose side effects were INTense. I was not expecting this. I've been on the chemo merry go round for years, and this was one of the hardest ever to go through.

I was knocked out for five straight days - today is my first day up. I have mets in the liver - within 2 hours of infusion, it felt like my liver swelled alot, pressed on my stomach and stayed that way until yesterday. So, 4-5 days. Something is still pressing, but not as much.

I was very, very weak - unable to support my own weight. Vertigo at night and am from days 3-5. Strong headaches days 1-5.

I feel much better today, and too hope this is a good sign. I haven't heard of anyone having s/e's like this on tdm1. I will let the trial people know - but wanted to ask here as well.

I, too, felt like it means it working. For me, it felt like I had literally ingested a poison with this first dose of tdm-1.

Did anyone else get any s/e's close to this?

Thanks -

Kim