HER2 Support Group Forums - View Single Post - Meta Analysis of Ki-67

R.B. · 06-04-2007, 03:12 AM

Less omega six + more omega three = less Ki-67

RB

http://www.leaonline.com/doi/abs/10....journalCode=nc

Tumor prostaglandin E2 concentrations were reduced by feeding the lower LA level; further dose-dependent decreases occurred in the DHA dietary groups and were accompanied by reduced levels of 12- and 15-hydroxyeicosatetraenoic acids. These changes in eicosanoid biosynthesis may have been responsible for the observed decreases in cell proliferation, indicated by suppressed Ki-67 expression, and increases in apoptotic activity, as reflected in TdT-mediated dUTP nick end labeling immunohistochemical staining.

06-04-2007, 03:12 AM	#3
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Less omega six + more omega three = less Ki-67 RB http://www.leaonline.com/doi/abs/10....journalCode=nc Tumor prostaglandin E2 concentrations were reduced by feeding the lower LA level; further dose-dependent decreases occurred in the DHA dietary groups and were accompanied by reduced levels of 12- and 15-hydroxyeicosatetraenoic acids. These changes in eicosanoid biosynthesis may have been responsible for the observed decreases in cell proliferation, indicated by suppressed Ki-67 expression, and increases in apoptotic activity, as reflected in TdT-mediated dUTP nick end labeling immunohistochemical staining.