My Onc does markers for stage 4 as a part of the overall picture. She says that they are unreliable accept as a piece of the big picture. I had markers done at the time of diagnosis and they were normal and as I turned out to be stage 3b I do not have much faith in them. I think they can be useful in being an indicator as to when to start looking deeper but if they were normal at stage 3 I would not count on them.
Alice
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