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One of the largest studies was done to look at estrogen and progesterone was the WHI. It would seem logical that most of those women would have taken premarin or prempo, synthetic forms of hormone replacement, since these are the most popular in the USA for HRT. However, I'm not sure. In the WHI, the mix of estrogen and progesterone were had more bc related events than estrogen alone.
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Robin
2002- dx her2 positive DCIS/bc TX Mast, herceptin chemo
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