Re: Genetic differences in enzyme CYP2D6 play a key role in effectiveness of tamoxife
So.. this most recent study is finding a significant correlation between the gene variant and tamoxifen metabolism? Looking back at the past threads I had interpreted previous studies as not finding a significant correlation? Does this open the door again on CYP2D6 testing, especially for Her2+ populations? My oncologist never mentioned this issue at all, I only learned of the gene alteration from this and other discussion boards. I'm torn on how hard to push for this test as I'm premenopausal and it would open up a Pandora's box of issues if tamoxifen is not an option.
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