HER2 Support Group Forums - View Single Post - Novel drug may be the answer in battling resistance in aggressive breast cancer

donocco · 10-07-2019, 12:38 PM

I could not find to much info about BOS172722. Apparently the human trials are just starting. They are going to combine it with IV Taxol to see the effect on cancers, particularly triple negative breast cancers. Apparently the drug, by interfering with the spindle fibers causes a speeding up of mitosis. Without the drug the mitosis takes about 52 minutes. With the BOS172722 it is sped up to 11 minutes, too fast for the proper lining up of the chromosomes

Paul

10-07-2019, 12:38 PM	#2
donocco Senior Member Join Date: Oct 2013 Posts: 474	Re: Novel drug may be the answer in battling resistance in aggressive breast cancer I could not find to much info about BOS172722. Apparently the human trials are just starting. They are going to combine it with IV Taxol to see the effect on cancers, particularly triple negative breast cancers. Apparently the drug, by interfering with the spindle fibers causes a speeding up of mitosis. Without the drug the mitosis takes about 52 minutes. With the BOS172722 it is sped up to 11 minutes, too fast for the proper lining up of the chromosomes Paul