[Lala]

I started out at 3600mg Xeloda and 1250mg Tykerb but had to lower the doses due to the side effects. The hand and foot syndrome and diarrhea were no fun. I am currently on a dose of 2500mg of Xeloda and 1000mg of Tykerb. My Xeloda schedule is 1 week on 1 week off.

I have found that the lower doses are easier to handle; but the schedule of Xeloda makes it even better. In addition I use a diet that helps avoid diarrhea and I do take the daily imodium as a back up. I have heard of doses of Xeloda at 2000mg being as effective as higher doses with out the toxicity. For me the main problem was the Xeloda dose being way too high.
I know I am continuing to respond at the lower doses so that eases my mind.