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I looked at my CT scan yesterday... I'm not sure what to make of it, but the progression I keep thinking is the mets in my spine. I have recently started to really hurt in my back. Maybe you are right about the Herceptin tumor site pain. Since I started Herceptin, I felt the pain in my back just increasing. However, the tumors are looking pretty yuckie. I kinda feel like one of the previous treatments might be a good idea because it was over 2 years ago, and because the tumors are in the same places... just with more frequency. The stuff in my liver originated from the one largest spot I had, the stuff in my back is in the places that were radiated (mostly). So logically, if it's the same stuff that went into hybernation, why not use like my 1st stage 4 treatment that knocked it out in 3 months?
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Jan04: Bilateral Mastectomy at age 28
Initial DX: Left Breast: IDC 2cm, Grade 3, HER2+3, 0 Nodes +, ER/PR-. Right Breast: Extensive DCIS ER-/PR+; Stage 1-2a
Feb04-Apr04: 4 AC, dose dense
Aug 04: 4 Taxotere
Dec 05: Bone and Liver METS; Stage 4. Carboplatin/Taxol/Herceptin. DX with Li-Fraumeni Syndrome
Apr 06: NED, maintenance Herceptin
Apr 07: CA1503=14; masses in liver; Xeloda/Tykerb
Nov 07: NED, Tykerb maintenance
Sept 08: Liver mets again, on Tykerb/Xeloda again, CA=19 and 27
Nov 08: Progression, Tykerb/Gemzar, CA=25
Dec 08: Progression, Herceptin/Navelbine, CA=40, 57, and 130
Jan 09: Progression in bone, recession in liver, Herceptin/Carbo/Abraxane CA=135
June 09: CA27/29=24, chemo break
Sept 09: Progression, CA=24, waiting on clinical trial (4 weeks no treatment)
Nov 09: now have brain mets, trial "on hold", getting 14 WBR treatments starting 11/2/09
Dec 09: possible start on p53 trial
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