HER2 Support Group Forums - View Single Post - Exercise and hormones postmenopausal women

R.B. · 06-10-2007, 11:39 AM

As with pre menopausal exercise reduces estradiol etc which is the target of the aromatase inhibitors as best I understand it.

(I came across this looking for something else as usual)

RB

Relation of BMI and physical activity to sex hormones in postmenopausal women.
McTiernan A, Wu L, Chen C, Chlebowski R, Mossavar-Rahmani Y, Modugno F, Perri MG, Stanczyk FZ, Van Horn L, Wang CY; Women's Health Initiative Investigators.

Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Cancer Prevention Research Program, Seattle, WA

Abstract

BMI was positively associated with estrone (beta = 0.031, p < 0.001), estradiol (beta = 0.048, p < 0.001), free estradiol (beta = 0.062, p < 0.001), free testosterone (beta = 0.017, p = 0.02), and prolactin (beta = 0.012, p = 0.02) and negatively associated with SHBG (beta = -0.02, p = 0.001). Total physical activity (metabolic equivalent tasks per week) was negatively associated with concentrations of estrone, estradiol, and androstenedione (beta = -0.006, -0.007, and -0.005, respectively, all p < or = 0.05).

06-10-2007, 11:39 AM	#1
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Exercise and hormones postmenopausal women As with pre menopausal exercise reduces estradiol etc which is the target of the aromatase inhibitors as best I understand it. (I came across this looking for something else as usual) RB Relation of BMI and physical activity to sex hormones in postmenopausal women. McTiernan A, Wu L, Chen C, Chlebowski R, Mossavar-Rahmani Y, Modugno F, Perri MG, Stanczyk FZ, Van Horn L, Wang CY; Women's Health Initiative Investigators. Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Cancer Prevention Research Program, Seattle, WA Abstract BMI was positively associated with estrone (beta = 0.031, p < 0.001), estradiol (beta = 0.048, p < 0.001), free estradiol (beta = 0.062, p < 0.001), free testosterone (beta = 0.017, p = 0.02), and prolactin (beta = 0.012, p = 0.02) and negatively associated with SHBG (beta = -0.02, p = 0.001). Total physical activity (metabolic equivalent tasks per week) was negatively associated with concentrations of estrone, estradiol, and androstenedione (beta = -0.006, -0.007, and -0.005, respectively, all p < or = 0.05).