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When I first started, the diarrhea was so bad, I became dehydrated. I had IV fludis for 2 days. I went off both drugs for a couple of weeks. This time around, my dr. lowered the Tykerb dosage (kept the already low-dose Xeloda) and I'm now doing fine. I average about 1 immodium every 3-5 days. But if I eat fried food, it's a problem. That's not a big deal since I eat very little of it anyway.
Best of luck,
Susan
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