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"Dr Javier Menendez, of Northwestern University Feinberg School of Medicine in Chicago, said oleic acid blocks the action of a cancer-causing oncogene called HER-2/neu which is found in about 30 percent of breast cancer patients."
"They found that oleic acid not only suppressed the action of the oncogene, it also improved the effectiveness of the breast cancer drug Herceptin, a targeted therapy made by Swiss drug maker Roche Holding AG (ROG.VX) that works against the HER-2/neu gene."
These studies were based on oleic acid's effect on individual cells, but mice studies are planned.
URL=http://www.washingtonpost.com/wp-dyn/articles/A62640-2005Jan10.html
This seems to be part of a larger research project studying the effect of fatty acids on HER2 cancer. In the past year, Dr. Menendez has also published articles showing that gamma linolenic acid (found in evening primrose oil) and alpha linolenic acid (found in flaxseed and canola oil) may help increase the chemo sensitivity of HER2 cancers to taxotere and navelbine and that the combination of the two fatty acids may even kill HER2 cells. I hope he plans to test these things in mice as well.
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