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Re: TDM-1 side effects
Kim
When I met with my doctor on Thursday for my infusion they said that the swelling in my liver and abdomen is a response to the treatment. I also experienced swelling when I was on herceptin and Abraxaine. The swelling has gone down significantly on this third round. Feel like I have lost 10 pounds between loosing all the fluid and reduction in swelling. My liver enzymes are we're also high prior to his infusion, but always seem to go down by the next week when they take my labs again.
My side effects this time were dry mouth and fatigue on Friday. They have to give me pretty strong premeds before the infusion because i am allergic to herceptin. I have been sleeping since Thursday. Today I woke up with a backache and a mild headache. I am trying to resist taking the steroids as they really do a number on me. The doctor said if headaches get worse to take some. All in all the side effects have been better so far on this third infusion. The doctor also stressed to eat more protein as it ill improve swelling and energy level.
Angie
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Diagnosed Stage IV Breast Cancer in August 2011 Her2+ Er-pr-
Metastic to liver
8 rounds Abraxaine (3 weeks on 1 week off) and Herceptin (once weekly)
April 2012 stopped Abraxaine, Herceptin only every three weeks. (liver and breast tumors shrank considerably but not NED)
June 2012 CT scan showed enlarged axillary lymph node not responding. Biopsy of node revealed same cancer. Surgeon recommended breast MRI. MRI revealed new area in left breast 6mm. Breast biopsy revealed same cancer. Surgeon not sure if we should do surgery.
7/29/12 CT scan to see if spreading anywhere else. Awaiting results to determine plan of care. Will meet with oncologist 8/7/12
8/7/12 no progression in liver. No evidence of disease anywhere else. Dr recommending TDM1 trial in Nashville. Waiting.
9/18/12 Began TDM1 in Nashville. Hopeful!!
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