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Old 08-10-2013, 08:31 AM   #1
thickdescription
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Join Date: Jan 2013
Location: Washington, DC
Posts: 24
Olive oil synergistically enhances Herceptin

Hi folks

I know there was a thread on this back in 2006, but I wanted to check in to see if anyone has any new information about how much olive oil daily is necessary to enhance Herceptin.

Background
There seems to be solid research that shows that oleic acid (Omega 9 fatty acid found in olive oil) significantly enhances the effects of Herceptin.

"To our knowledge this is the first report that a dietary monounsaturated fatty acid previously suggested to be protective against breast cancer significantly down-regulates the expression of Her-2/neu, cutting it by up to 46%," lead researcher, Javier Menendez, from the Northwestern University Feinberg School of Medicine in Chicago, noted in a statement."Moreover, in our tests, oleic acid's inhibition of Her-2/neu synergistically interacted with Herceptin-based immunotherapy by promoting the death of breast cancer cells exhibiting high levels of the oncogene
http://www.virtualmedicalcentre.com/...astuzumab/5505

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1878493/

My question is - how much olive oil daily is necessary to achieve this effect? Can anyone point me to research-based recommendations?

One might suppose that the more the better, but I want to balance this with the WINS diet - which shows a 40% increased survival rate for a very low fat diet.

By the way, I did some research on olive oil and found that the UC Davis olive oil center found that there are significantly different levels of quality in commercially available extra virgin olive oil available in the US. The highest quality olive oil they found with high levels of all the good stuff was California Olive Ranch Extra Virgin. Luckily, this is available both online and at my local Safeway.

Here's the link to the UC Davis report. http://www.olivecenter.ucdavis.edu/f...%20reduced.pdf
__________________
DX Dec 2012: ER-/PR- HER2+
Stage 1, Grade 3
Lumpectomy Feb 1: 6 of 6 nodes clear
Re-excision Apr 5: no malignancy.
6 3-wkly cycles of Carboplatin/Taxotere from 5/10/13
Herceptin for one year from 3/28/13
Radiation X 37
Herceptin related cardiotoxicity: ACE inhibitors and Beta blockers prescribed
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