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Old 02-19-2016, 10:08 AM   #27
agness
Senior Member
 
Join Date: Aug 2014
Location: Seattle, WA
Posts: 285
Re: HER2 and Immunotherapy Studies for reference

This one is a little older so it is a little dated. What I liked about it is the explanation of active versus passive immunotherapy strategies and also understanding why melanoma is being pursued as a first target with anti PD-1 therapies now such as Opdivo and Keytruda.

Someone on Inspire.com is in a trial right now using passive t-cell immunotherapy, though using her own tumor infiltrating lymphocytes greatly expanded in number outside of her body and they re-administered after they flattened her immune system as they do with leukemia patients. It is working though, she was really sick before and tumors are shrinking and starting to go away. The study is being done in Bethesda.

Adoptive T cell therapy for cancer in the clinic

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1878537/
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