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Anne,
In my experience, No. Altho' my CA27-29 was in the high 300's when dx'd with other mets, then down to normal after scans showed NED, my recurrances of brain mets have always been while CA27-29 is around 17. And still NED in body.
From all I have researched in the past four yrs, MRi with contrast (even the triple contrast/smaller slice pics) is the definitive set of scans for brain mets.
The question does remain whether the MRispec/something (or even pet) could determine between 'active' cancer or necrosis, tho'.
But for dx or good checkups, it is the MRi with contrast by far.
pattyz
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