HER2 Support Group Forums - View Single Post - Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastases)

marvass · 09-25-2015, 11:04 AM

Carol is still doing fine. She now gets the IT and IV treatment of herceptin every 3 weeks, 150mg IT with hydrocortisone, and 6mg per kilo IV. No new mets developed and older ones under control. Hope this ONT-380 with TDM1 gets approval soon. A pill would be much better than IT, with the risks it has, especially with the big risk of meningitis.

It is nearly 5 years now since the 2cm brain tumor was treated with local radio therapy, and 4 years since it come back into several spots again treated locally! It is nearly 3 and a half years since we started IT herceptin.

So those of you fighting brain mets do not give up.

09-25-2015, 11:04 AM	#202
marvass Senior Member Join Date: May 2012 Posts: 105	Re: Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastase Carol is still doing fine. She now gets the IT and IV treatment of herceptin every 3 weeks, 150mg IT with hydrocortisone, and 6mg per kilo IV. No new mets developed and older ones under control. Hope this ONT-380 with TDM1 gets approval soon. A pill would be much better than IT, with the risks it has, especially with the big risk of meningitis. It is nearly 5 years now since the 2cm brain tumor was treated with local radio therapy, and 4 years since it come back into several spots again treated locally! It is nearly 3 and a half years since we started IT herceptin. So those of you fighting brain mets do not give up.