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Jean,
I recall reading two years ago about a concept for an AI that would specifically target the ER in the breast, which seems to be what is needed here. I have been disappointed not to see anything further on this; perhaps the research Lani has posted here will renew interest in it. Such a drug would be a huge boon to ER+ bc patients, allowing us to keep our bones (and our sex lives) intact while delivering the tx we really need.
Hopeful
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