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Our brave and beloved Amanda has died. The ripples from her indomitable spirit and her devotion to her family will truly be felt all around the world.
So much grief.....
Pam

__________________
Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.

10-11-2013, 05:37 PM	#1
Pamelamary Senior Member Join Date: Apr 2012 Location: Melbourne, Australia Posts: 494	Rest in peace, Mandamoo. Our brave and beloved Amanda has died. The ripples from her indomitable spirit and her devotion to her family will truly be felt all around the world. So much grief..... Pam __________________ Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+, C-erbB-2 status 3+. Clear margins, no nodal involvement. Radiotherapy, i year Tamoxifen, 4 years Arimidex. Rediagnosed 2012: Multiple bone metastases. 3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo. 5/12:Unexpected development of numerous bilateral liver mets. Came off trial. Started Docetaxol/ Herceptin + Zometa. 8/12:Bones stable +major regression in liver (!) 9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers! Changed to Denosumab. 11/12: Scan shows stable - yay! 11/13: Still stable :-) !!! 1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly. 2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.