HER2 Support Group Forums - View Single Post - Chloroquine

CourtneyL · 09-29-2011, 03:17 PM

Hi All - I recently read this article in Cure magazine talking about the common anti-malarial drug, Chloroquine, as a potential destroyer of cancer stem cells. It all sounds very promising. There will soon be a multicenter clinical trail using it in triple negative bc:

http://curetoday.com/index.cfm/fusea...rticle_id/1749

Intrigued by the article, I did some further research and found some promising preliminary studies such as this one, discussing Chlroquine as a HER2 disruptor:

http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=40c77acf-0078-45fa-bd01-043689aa3ff6&cKey=6ca9e87b-b447-4fb2-9f67-60f3e7edb3bf&mKey={0591FA3B-AFEF-49D2-8E65-55F41EE8117E}

So should I plan a trip to Africa so I can get my Chloroquine prescription now? Why not? Its already FDA approved. I've got half a mind to just try this out myself. Does anyone have any experience with this or thoughts? I took this drug years ago when traveling through Central America and other than a few lucid dreams, it really didn't seem to have any negative side effects.

09-29-2011, 03:17 PM	#1
CourtneyL Senior Member Join Date: Aug 2008 Location: San Francisco Posts: 260	Chloroquine - Sounds promising! Hi All - I recently read this article in Cure magazine talking about the common anti-malarial drug, Chloroquine, as a potential destroyer of cancer stem cells. It all sounds very promising. There will soon be a multicenter clinical trail using it in triple negative bc: http://curetoday.com/index.cfm/fusea...rticle_id/1749 Intrigued by the article, I did some further research and found some promising preliminary studies such as this one, discussing Chlroquine as a HER2 disruptor: http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=40c77acf-0078-45fa-bd01-043689aa3ff6&cKey=6ca9e87b-b447-4fb2-9f67-60f3e7edb3bf&mKey={0591FA3B-AFEF-49D2-8E65-55F41EE8117E} So should I plan a trip to Africa so I can get my Chloroquine prescription now? Why not? Its already FDA approved. I've got half a mind to just try this out myself. Does anyone have any experience with this or thoughts? I took this drug years ago when traveling through Central America and other than a few lucid dreams, it really didn't seem to have any negative side effects. __________________ 4/17/08: Dx Stage IV at age 30 - extensive mets to liver, lungs, and bones. Er/Pr-, Her2+++ April 08-Aug 08:Taxotere, Cytoxan, Herceptin, Zometa - complete response! Sept 08-Dec 08: Herceptin +Zometa for maintenance. Jan 09-April 09: Brain mets. Add Tykerb. Watch and wait. April 09: Gamma Knife 10 brain mets, add Xeloda. Sept 09: Gamma Knife to 1 brain met. Nov 09- April 10: Lung progression, add Gemzar to Herceptin, Zometa. May 10- Sept 10: HER2 Vaccine Trial Sept 10: Add Tykerb for more brain mets. Oct 10: Gamma Knife to 7 brain mets. Dec 10: Switch from Zometa to Denosumab. Jan 11: Gamma Knife to 3 brain mets. March 11: Gemzar/Herceptin for lung/bone progression. April 11: More brain mets - Intrathecal Herceptin June 11: Ixempra/Herceptin for lung, soft tissue progression. Aug 11: Gamma Knife Sep 11: Abraxane/Herceptin Future: NED Send me a PM if you'd like to follow my journey on Caringbridge.