[chrisy]

I've had some info posted on other threads, thought I'd better put it here where it "belongs"!

As reported earlier, my first treatment was pretty rough, but my 2nd and 3rd treatments were much easier than the initial one.

I am pretty wiped out the evening of treatment, and with #2 I had a low grade fever and headache for a couple of days. After treatment #3 I was still wiped that evening but did not have any aches or fever at all.

Still haven't seen my liver enzymes come down significantly - they are living at between 2-3x ULN for AST, ALT and Alk Phos. At least they haven't continued to go up, but it would be nice to get back closer to normal.

Platelets crash on day 8 but still rebound the next 2 weeks, all as expected.

Seems like all the trials for this one are filling up. I'm on the 3 week trial, and was told it is almost full.

As for response, I had scans after 5 weeks and the fast growing lesions in my liver are significantly less metabolically active, which is good, and some of the "new" ones that had shown up between Jan 2 and Jan 31 are no longer visible on the March 19 scan. All in all, this is the right direction for things to be going, especially as I was off all treatment for nearly a month!