HER2 Support Group Forums - View Single Post - Does radiation makes the tumor not responsive to chemo?

Julie2 · 09-03-2011, 05:57 PM

Hi All,

I progressed on Navelbine,Tykerb,TDM1 and Xeloda. I have mets in lungs and a mammary node. I just started Gemzar and also looking into local targeted radiation. The radiation oncologist said all my tumors are amenable to radiation. He would like to do more conventional radiation to mammary node and Cyberknife to lungs, but the insurance approval is a big holdup.
My question is will the radiation makes the tumor not responsive to chemo later(in case if the same tumor progresses)? Or what other risks are involved in radiation or Cyberknife?

Thanks,
Julie

09-03-2011, 05:57 PM	#1
Julie2 Senior Member Join Date: Sep 2005 Posts: 556	Does radiation makes the tumor not responsive to chemo? Hi All, I progressed on Navelbine,Tykerb,TDM1 and Xeloda. I have mets in lungs and a mammary node. I just started Gemzar and also looking into local targeted radiation. The radiation oncologist said all my tumors are amenable to radiation. He would like to do more conventional radiation to mammary node and Cyberknife to lungs, but the insurance approval is a big holdup. My question is will the radiation makes the tumor not responsive to chemo later(in case if the same tumor progresses)? Or what other risks are involved in radiation or Cyberknife? Thanks, Julie __________________ Diagnosed in Sept 2004 while pregnant with the second child. Stage 3b, tumor 4.5cm, 4 auxillary and supraclav node positive. Her2+++ FISH 9.4 and er-,pr-. Had dose dense neoadjuvant AC,Taxol then mastectomy,radiation+xeloda+Herceptin.