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DianneS · 02-27-2012, 07:13 PM

Ok, I admit I should know this, but have never gotten an clear and understandable answer from my onc. Can anyone tell me what this means?? Could it mean the tumor is 1.0 cm that is IDC and 1.0 cm DCIS?

My path report says:

'Poorly differentiated infiltrating ductal carcinoma compatible with 8/9 points according to the SBR grading system (tubule formation 3, nuclear grade 3, mitotic rate 2) This is associated with high grade ductal carcinoma in situ with comedonecrosis. The in situ component constitutes approximately 50% of the tumor volume and focally exceeds the area of invasive carcinoma by several millimeters. The invasive carcinoma focally approaches the painted surgical margin up to 1 mm and the in situ component is present within a fraction of a millimeter of the painted surgical margin.'

Ok, so I get the part down to where it says this is high grade ductal carcinoma in situ etc etc. If the DCIS is 50% of the tumor doesn't that change the size of the tumor? In total it is 2.1 cm. Isn't DCIS normally a better prognosis or does it not matter since there was IDC...I am confused.

Thank you for any answers!!

dianne

02-27-2012, 07:13 PM	#1
DianneS Senior Member Join Date: Aug 2008 Posts: 327	Idc/dcis question Ok, I admit I should know this, but have never gotten an clear and understandable answer from my onc. Can anyone tell me what this means?? Could it mean the tumor is 1.0 cm that is IDC and 1.0 cm DCIS? My path report says: 'Poorly differentiated infiltrating ductal carcinoma compatible with 8/9 points according to the SBR grading system (tubule formation 3, nuclear grade 3, mitotic rate 2) This is associated with high grade ductal carcinoma in situ with comedonecrosis. The in situ component constitutes approximately 50% of the tumor volume and focally exceeds the area of invasive carcinoma by several millimeters. The invasive carcinoma focally approaches the painted surgical margin up to 1 mm and the in situ component is present within a fraction of a millimeter of the painted surgical margin.' Ok, so I get the part down to where it says this is high grade ductal carcinoma in situ etc etc. If the DCIS is 50% of the tumor doesn't that change the size of the tumor? In total it is 2.1 cm. Isn't DCIS normally a better prognosis or does it not matter since there was IDC...I am confused. Thank you for any answers!! dianne __________________ Three years and 5 months NED Dx: Aug 2008 right breast IDC with 50% of tumor DCIS, Stage II or IIA, tumor size: 2.1 cm Grade 3 8/9 Richardson/Bloom test ER+ weakly positive Alred Score: 4 (suggesting I would strongly benefit from hormone therapy) PR-, HER2 positive +++ No vascular invasion No lymph nodes involved Surgery: Sept. 9, 2008 -Modified radical mastectomy, right breast. I chose to have a simple mastectomy on the left. Began Taxotere/Carboplatin/Herceptin November, 2008. Finished T/C March 2009. Finished #16 Herceptin Sept. 09. AI's and Tamoxifen made me sick. Began natural Tamoxifen which is Quercetin, I3C and a combo of other supplements. I am also a DES Daughter. There is now a link between DES exposure in utero and breast cancer!