HER2 Support Group Forums - View Single Post - My Onc wants to stretch out Herceptin infusions

Hopeful · 06-02-2016, 06:50 AM

Here is a link to an abstract about the clinical pharmacology of Herceptin: http://www.ncbi.nlm.nih.gov/pubmed/18690878

It states the half-life of Herceptin as 28 days. The half-life of a substance is the period of time required for the concentration or amount of drug in the body to be reduced by one-half.

So, at 21 day intervals, you are maintaining a somewhat higher overall concentration of Herceptin in the body than at 28 day intervals. Neither is long enough for the drug to be completely out of the body.

Hope this is helpful.

Hopeful

06-02-2016, 06:50 AM	#5
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Re: My Onc wants to stretch out Herceptin infusions Here is a link to an abstract about the clinical pharmacology of Herceptin: http://www.ncbi.nlm.nih.gov/pubmed/18690878 It states the half-life of Herceptin as 28 days. The half-life of a substance is the period of time required for the concentration or amount of drug in the body to be reduced by one-half. So, at 21 day intervals, you are maintaining a somewhat higher overall concentration of Herceptin in the body than at 28 day intervals. Neither is long enough for the drug to be completely out of the body. Hope this is helpful. Hopeful